Know the Difference Between Children's MOTRIN® & TYLENOL® for Infants

Infants' Motrin Eight Hour relief and Infants' Tylenol for Fever & Pain

Children’s TYLENOL® and Children’s MOTRIN® work differently to relieve your child’s pain and/or fever because they contain different active ingredients. Make sure you know the difference between these products so you can choose the medication that may be the most appropriate for your child.

Infants' TYLENOL® Infants' MOTRIN®
What is the active ingredient?
Medicine bottle icon
When should I use them?
Use as a first line of defense against pain or fever.
Temperature icon for fever
Try Infants’ MOTRIN® should pain or fever persist as the two actives work differently.
How long can it last?
Infants’ TYLENOL® is dosed every 4-6 hours.
Stopwatch icon
Infants’ MOTRIN® relieves fever for up to 8 hours, helping your child get through the day or night.
How could it affect my child’s tummy?
Gentle on the tummy.
Stomach icon
May cause some irritation to sensitive tummies.
What is the dosing system?
Infants’ TYLENOL® SIMPLEMEASURE® design creates less mess with improved dosing accuracy.
White Syringe Icon
For accurate dosing, use the oral syringe included.


© Johnson & Johnson Inc. 2017

To be sure either of these products are right for your child, always read and follow the labels.

Dosing schedule does not equal length of pain or fever relief.

*Children’s oral analgesics, 2015, Rogers Healthcare Group Surveys on OTC Physician Counselling and Recommendations

†Reduces fever up to 8 hours

White Separator Line

Infants’ TYLENOL® Drops

Trusted by doctors and parents for over 50 years to relieve fever and pain.


Things to watch out for.

These five symptoms can mean a more serious infection.