Skip to main content

Join Care Club Canada today and receive $5 off your next purchase. Terms and conditions apply. Click for details.

Topical Lidocaine: What Is It and How Does It Work for Pain Relief?

Lidocaine (pronounced lie-doh-kayn) is a medication that can be applied topically (to the skin) to temporarily relieve pain. It is an active ingredient that’s found in many over-the-counter (OTC) and prescription topical pain relievers.1

Two young women jogging together on a bridge, enjoying an active workout.

What Is Lidocaine?

Lidocaine is a medication that numbs the area in which it’s applied. It is in a class of medications called anaesthetics. When lidocaine is applied to the skin to relieve pain, it’s known as a topical analgesic (pain reliever).2


Lidocaine can come in many different dosage forms, such as:1

  • Creams

  • Gels

  • Ointments

  • Sprays

  • Patches

How Does Lidocaine Work?

Lidocaine can relieve many different types of pain by blocking pain signals sent from nerves in the skin. When targeting nerves to block pain signals, it creates a numbing sensation or a temporary loss of feeling.1

Unlike orally ingested pain relievers, such as acetaminophen (TYLENOL®), you can control how topical lidocaine targets your pain. When applied to your skin, it gives you pain relief only in the area that you apply it.

What Is Lidocaine Used For?

Topical lidocaine can be used to temporarily relieve pain. It can be used on the following areas:3

Back & Shoulders

Back & Shoulders

Knees, elbows and ankles

Knees, elbows and ankles

Legs & Hips

Legs & Hips

Small Joints

Small Joints

Topical Lidocaine Benefits

Topical analgesics have several potential benefits. They include:4

  • Targeted pain relief — topical pain relievers such as lidocaine allow you to apply pain relief directly to the specific area where you need it the most

  • Provides another form of pain relief other than oral medication — topical lidocaine is well recognized as an effective option for the management of acute pain5

How To Use Lidocaine

Lidocaine is a topical pain reliever that you apply directly to your skin. Use it exactly as your doctor instructs or as listed on the package.1

Unless otherwise instructed by your doctor, don’t apply topical lidocaine to irritated skin or skin with blisters, rashes, infections, or cuts.

You can apply a thin layer of lidocaine directly to clean dry skin.

Wash your hands before and after application to avoid numbness in your fingers.

Lidocaine and Other Topical Pain Reliever Ingredients

Topical pain relievers come in many forms (creams, gels, sprays, and patches) and there are several options available:

Lidocaine — is a topical analgesic that provides numbing relief for your aches and pains by blocking the signals of the nerve endings in the skin.

Diclofenac sodium — an NSAID (non-steroidal anti-inflammatory drug) found in many rub-on treatments. When absorbed into skin, it works to reduce inflammation.

Methyl salicylate — (oil of wintergreen) has a minty smell and creates a cooling sensation when applied to skin acting as a distraction to pain points.

Capsaicin — a compound found in chili peppers that produces a warming sensation.

Menthol — (mint camphor) causes a cooling sensation and that feeling desensitizes the nerve endings. Like ice packs, menthol decreases peripheral arterial blood flow.

Introducing PRECISE from the Makers of TYLENOL 

Lidocaine is the primary active ingredient in PRECISE pain relief creams. Learn more about our PRECISE pain relief creams by clicking here.

FAQs

Yes, lidocaine cream may cause a loss of feeling that numbs the skin in the application area. The numbing effect can relieve pain by stopping your nerves from sending pain signals.1

Yes, lidocaine does expire. You shouldn’t use lidocaine after the expiration date. See the expiration date on the package to find out when your product will expire.

References

  1. Lidocaine (Topical Application Route). Mayo Clinic. Updated May 1, 2023. Accessed May 30, 2023, https://www.mayoclinic.org/drugs-supplements/lidocaine-topical-application-route/description/drg-20072776
  2. Lidocaine Skin Cream or Ointment. Cleveland Clinic. Accessed May 31, 2023, https://my.clevelandclinic.org/health/drugs/19854-lidocaine-skin-cream-or-ointment
  3. External analgesic drug products for over-the-counter human use: tentative final monograph. FDA. Fed Regist. 1983;48(27):5852. Accessed May 29, 2023, https://tile.loc.gov/storage-services/service/ll/fedreg/fr048/fr048027/fr048027.pdf
  4. Voute M, Morel V, Pickering G. (2021). Topical Lidocaine for Chronic Pain Treatment. Drug design, development and therapy. 2021; 15, 4091–4103, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487862/
  5. Lidocaine and Pain Management in the Emergency Department, https://pmc.ncbi.nlm.nih.gov/articles/PMC3961016
  6. Topical Pain Relief: What Is It + How Does It Work?, https://health.clevelandclinic.org/topical-pain-relief-what-is-it-and-how-does-it-work/

Links to other parties’ articles and websites are provided for convenience only. Kenvue Canada Inc. is not responsible for their content.

Related Products

*2023 IQVIA study in Adult Analgesics